Diverse effects of acute and chronic administrated levothyroxine on the morphine withdrawal syndrome in male mice
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چکیده
همدقم : ي رييغت يديئوريت ياهنومروه نازيم نيفرم هب هتسباو دارفا رد هتفا تـسا هدـش شرازـگ ديئوريت و زيفوپيه سوملااتوپيه روحم تيلاعف صوصخ رد يتوافتم جياتن و . رد غت هعلاطم نيا يي لاعف تار ي ت هدغ ت ي ئور ي ول نمزم و داح زيوجت اب د تفرگ رارق يسررب دروم نيفرم عطق مئلاع رب نيسكوريتو . شور اه : 42 رد غلاب رن يهاگشيامزآ ديفس شوم 6 دش هدافتسا هورگ . نيسكوريتوول هدننك تفايرد ياههورگ يقافص لخاد mg/kg 5 / 0 ) نمزم ،داح تروصب 4 و هزور نمزم 16 هزور ( و هاش ياههورگ د زور راهچ تدم رد نيفرم طسوت يگمه ) mg/kg 20 ، 40 و 80 ( ديدرگ ءاقلا نيفرم عطق مردنس هديدپ ناسكولان طسوت و هدش داتعم . عـطق مردنس مئلاع تدم هب نزو شهاك و شرپ ،هراويد زا دوعص ،اپ ود يور نداتسيا لماش 30 هزادنا هقيقد دش يريگ . هتفاي اه : داد ناشن جياتن هك شيازفا ار نيفرم عطق مردنس مئلاع داح نيسكوريتوول يم دهد . تدم هب نيسكوريتوول فرصم 4 هراوـيد زا دوعـص و شرپ دادعت شهاك ثعاب زور دش نزو شهاك راهم و . تدم هب نيسكوريتوول فرصم 16 داد شهاك ار اپ ود يور نداتسيا دادعت طقف زور . هجيتن يريگ : يم رظن هب فيعضت اي و ديدشت رد يديئوريت ياهنومروه نازيم رب رثا اب نيسكوريت دسر تدـم هـب هتسباو تروصب رثا نيا و هدومن رثا نيفرم عطق زا يشان مئلاع يم رييغت دباي .
منابع مشابه
Diverse effects of acute and chronic administrated levothyroxine on the morphine withdrawal syndrome in male mice
Introduction: Some studies indicate changes in the level of thyroid hormones in addicted people. Also, there are some reports concerning the modulation of hypothalamus-hypophysis-thyroid axis in the context of morphine addiction. In the present study, the effects of thyroid gland activation via the acute and chronic administration of levothyroxine on morphine withdrawal syndrome were investi...
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